University of Illiinois at Urbana-Champaign
Adjunct Professor for the University of Illinois Department of Chemistry.
Dr. Boulanger has worked for Abbott Laboratories, FMC, Medi-Chem, and Albany Molecular Research and is not your average chemist. He has many hobbies and broad training, much of which he employs at the company. As a machinist and engineer, he builds the company’s reactors, temperature controllers, stirrers, and many other pieces of company equipment. As a glassblower, he designs many pieces of glassware (You can find the “Boulanger trap” in the ACE Glass catalog, for instance.)
This broad background he brings to bear at the bench, as the company specializes in very difficult process and preparative chemistry. Frequently, the solution is not strictly in the chemistry, but the chemical engineering aspect of it, thus his solutions and methods are typically unorthodox.
Publications and Grants
"Stereochemical Control of Transpositional Allylic Oxidation" Philip Warner, William Boulanger, Thomas Schleis, Shih Lai Lu, Ziem Lee, and Suae-Chen Chang J. Org. Chem. 1978, 43, 4388-91.
"Double Bridgehead Olefins via Pyrolysis" William Boulanger and Philip Warner Tetrahedron Lett. 1980, 21(2), 123-6.
"Bridged Dienes: Synthesis of Bicyclo[4.3.1.] deca-1-5-diene" William Boulanger and Philip Warner Tetrahedron Lett. 1983, 24(39), 4165-8.
"5-(Halomethyl)-2-pyranones as Irreversible Inhibitors of a Chymotrypsin" William Boulanger and John Katzenellenbogen J. Med. Chem. 1986, 29, 1483.
"Structure-Activity Study of 6-Substituted-2-pyaranones as Inactivators of a Chymotrypsin" William Boulanger and John Katzenellenbogen J. Med. Chem. 1986, 29, 1159.
"An Improvement in the Synthesis of 1,2,4,9 Tetrahydrocarbazol-3-one" William Boulanger and Victoria Dolsen. Org. Prep. Proced. Int. 1993, 25(6), 707-8.
"Synthesis, Chromatographic Resolution, and Anti-Human Immunodeficiency Virus Activity of (+/-) Calanolide A and its Enantiomers" Michael T. Flavin; John D. Rizzo; Albert Khilevich; Alla Kucherenko; Abram K. Sheinkman; Vilayphone Vilaychack; Lin Lin; Wei Chen; Eugenia Mata Greenwood; Thitima Pengsuparp; John M. Pezzuto; Stephen H. Hughes; Tom M. Flavin; Michael Cibulski; William A. Boulanger; Robert L. Shone; and Ze-Qi Xu J. Med Chem. 1996, 39, 1303-1313.
"Synthesis of the Novel AntiAIDS Agent Calanolide A", grant 1R43AI34805-01 awarded by the National Institutes of Health via the SBIR 7/93. William A. Boulanger submitter and principle investigator.
“Total Synthesis of (S)-Equol” Heemstra, J.; Kerrigan, S.; Helfrich, W. T.; Boulanger, W. A. Submitted to Organic Letters 2/2006
U.S. 4,370,339 to Abbott Labs (January 25, 1983) "Method for Treating Inflammatory Conditions" Fortuna Haviv, Robert Denet, and William Boulanger
U.S. 6,043,271 (March 28, 2000) "Method for the Preparation of (+/-) Calanolide A and Intermediates Thereof" Michael T. Flavin, Ze-Qi Xu, John D. Rizzo, Alla Kucherenko, Albert Khilevich, Abram Kivovich Sheinkman, Vilayaphone Vilaychack, Lin Lin, Wei Chen, William Boulanger
William A. Boulanger Ph.D
Chairman & Executive Chemist