Publications and Presentations

Zeng, C.; Manion, B. D.; Benz, A.; Evers, A. S.; Zorumski, C. F.; Mennerick, S.; Covey, D. F. “Neurosteroid Analogues. 10. The Effect of Methyl Group Substitution at the C-6 and C-7 Positions on the GABA Modulatory and Anesthetic Actions of (3a,5a)- and (3a,5b)-3-Hydroxypregnan-20-one”. J. Med. Chem. 2005, 48, 3051-3059.

 

Shu, H.; Zeng, C.; Wang, C.; Covey, D. F.; Zorumski, C. F.; and Mennerick, S. “Cyclodextrins sequester neuroactive steroids and differentiate mechanisms that rate limit steroid actions”. British Journal of Pharmacology, 2007, 150, 164-175.

 

Tonkabon, R. D.; Hastings, W. R.; Zeng, C.; Akk, G.; Manion, B. D.; Bracamontes, J. R.; Steinbach, J. H.; Mennerick, S.; Covey, D. F.; Evers, A. S. “Photoaffinity Labeling of a Neuroactive Steroid Binding Site”. J. Biol. Chem. 2003, 278, 13196-13206.

 

Wang, M.; He, Y.; Eisenman, L.; Fields, C.; Zeng, C.; Mathews, J.; Benz, A.; Fu, T.; Zorumski, E.; Steinbach, J. H.; Covey, D. F.; Zorumski, C. F.; Mennerick, S. “3b-Hydroxypregnane Steroids Are Pregnenolone Sulfate-like GABAA-receptor Antagonists”. Journal of Neuroscience, 2002, 22, 3366-3375.

 

Ostlund, R. E.; McGill, J. B.; Zeng, C.; Covey, D. F.; Stearns, J.; Stenson, W. F.; Spilburg, C. A. “Gastrointestinal Absorption and Plasma Kinetics of Soy D5-Phytosterols and Phytostanols in Humans”. Am. J. Physiol. 2002, 282 (4, Pt. 1), E911-E916.

 

Mennerick, S.; Zeng, C.; Benz, A.; Shen, W.; Izumi, Y.; Evers, A. S.; Covey, D. F.; Zorumski, C. F. “Effects on GABAA Receptors of a Neuroactive Steroid That Negatively Modulates Glutamate Neurotransmission and Augments GABA Neurotransmission”. Molecular Pharmacology, 2001, 60, 732-741.

 

Zeng, C.; Benz, A.; Howell, M.; Manion, B.; Evers, A. S.; Zorumski, C. F.; Mennerick, S.; Covey, D. F. “Effect of C-6 and C-7 Methyl Substitution on Modulatory Action of Neuroactive Steroids at GABAA Receptors”. 222nd ACS National Meeting, Chicago, IL, August 25~29, 2001, MEDI-216.

 

Zeng, C.; Han, M.; Covey, D. F. “Neurosteroid Analogues. 7. A Synthetic Route for the Conversion of 5b-Methyl-substituted Analogues of Neuroactive Benz[e]indenes”. J. Org. Chem. 2000, 65, 2264-2266.

 

Zeng, C.; Shen, W.; Zorumski, C. F.; Covey, D. F. “Structure-Activity Studies of Steroid Inhibitors of NMDA Receptor Function”. 217th ACS National Meeting, Anaheim, CA, March 21~25, 1999, MEDI-117.

 

Zeng, C.; Midland, S. L.; Keen, N. T.; Sims, J. J. “Concise Syntheses of (+) and (-)-Syringolide 1 and (-)-D7-Syringolide 1”. J. Org. Chem. 1997, 62, 4780-4784.

 

Tsurushima, T.; Midland, S. L.; Zeng, C.; Ji, C.; Sims, J. J.; Keen, N. T. “Synthesis of Syringolide 1 Ketals and Esters for Receptor Studies”. Phytochemistry, 1996, 43, 1219-1225.

 

Zeng, C.; Lin, G.; Shen, H.; Zhang, S. “Studies on the Chemical Constituents of the Dayawan Bay Germ Pseudomonas Sp”. Chinese J. of Marine Drug, 1996, 15, 5-7.

 

Shi, Z.; Zeng, C.; Lin, G. “A Synthesis of the Polyhydroxylated Pyrrolidines: Synthesis of 1, 4-Dideoxy-1, 4-imino-D-lyxitol and N-Benzyl-4-epi-(-)-anisomycin”. Heterocycles, 1995, 41, 277-287.

 

Zeng, C.; Ishibashi, M.; Matsumoto, K.; Nakaike, S.; Kobayashi, J. “Two New Polycyclic Aromatic Alkaloids from the Okinawan Marine Sponge Biemna sp”. Tetrahedron, 1993, 49, 8337-8342.

 

Zeng, C.; Ishibashi, M.; Kobayashi, J. “Biemnasterol, a New Cytotoxic Sterol with the Rare 22, 25-Diene Side Chain, Isolated from the Marine Sponge Biemna sp”. J. Nat. Prod. 1993, 56, 2016-2018.

 

Ishibashi, M.; Zeng, C.; Kobayashi, J. “Keruffaride: Structure Revision and Isolation from Plural Genera of Okinawan Marine Sponges”. J. Nat. Prod. 1993, 56, 1856-1860.

 

Kobayashi, J.; Zeng, C.; Ishibashi, M.; Sasaki, T. “Luffariolides F and G, New Manoalide Derivatives from the Okinawan Marine Sponge Luffariella sp”. J. Nat. Prod. 1993, 56, 436-439.

 

Lin, G.; Zeng, C. “Synthesis of (3Z, 6Z)-9S, 10R-Epoxy-heneicosadiene. Huaxue Xuebao, 1993, 51, 197-201.

 

Kobayashi, J.; Zeng, C.; Ishibashi, M. “Keruffaride, a New Cyclopentanepentol-containing Metabolite from the Okinawan Marine Sponge Luffariella sp”. J. Chem. Soc., Chem. Commun. 1993, 79-81.

 

Zeng, C.; Ishibashi, M.; Kobayashi, J.; Sasaki, T. “Structures of Luffariolides F and G, New Sesterpenes from Okinawan Marine Sponge Luffariella sp”. 113th annual meeting of the Pharmaceutical Society of Japan, Osaka, JAPAN, March 29~31, 1993, 30DA.

 

Kobayashi, J.; Zeng, C.; Ishibashi, M.; Shigemori, H.; Sasaki, T.; Mikami, Y. “Niphatesines E~H, New Pyridine Alkaloids from the Okinawan Marine Sponge Niphates sp”. J. Chem. Soc., Perkin Trans. 1, 1992, 1291-1294.

 

Lin, G.; Zeng, C. “Synthesis of Sex Pheromone of Gypsy Moth via Sharpless Epoxidation of Divinylcarbinol”. Huaxue Xuebao, 1992, 50, 78-84.

 

Lin, G.; Zeng, C.In situ Aminolysis of 1, 2-Epoxy-penten-3-ol”. Chin. J. Chem. 1991, 9, 381-384.

 

Lin, G.; Shi, Z.; Zeng, C. “One-pot Synthesis of a, b-Dihydroxy Sulfides via Titanium-promoted Oxirane Ring Opening”. Tetrahedron: Asym. 1991, 4, 1533-1536.

 

Gu, H.; Zeng, C.; Wang, Z. “Synthesis of b-(2’-Norbornen-5’-yl) a,b-unsaturated Ketones and Aldehydes in the Presence of Phase Transfer Catalyst (PTC)”. Youji Huaxue, 1991, 11, 393-396.